Smoking III

I guess by now you're curious? The answer is, "lifelong non-smoker". ;-)

Smoking II

News about nicotine addiction:

Researchers say they have identified brain cell receptors that appear to be responsible for nicotine addiction, a finding of clear importance for smokers who are desperately trying to kick the habit.

The receptors normally are activated by acetylcholine, a molecule that carries signals between nerve cells and has multiple functions in the body. A large number of acetylcholine receptors have been identified, each with subunits adapted for a specific function. Twelve of those receptors also are activated by nicotine.

Smoking

It has long been said that cigarettes are addictive in the same way as heroin (sometimes misunderstood as cigarettes being as addictive as heroin, which they aren't) - and now, following up on similar results from animal studies, UM researchers help explain why:

It's the first time smoking has been shown to affect the human brain's natural system of chemicals called endogenous opioids, which are known to play a role in quelling painful sensations, heightening positive emotions, and creating a sense of reward. It's the same system that is stimulated by heroin and morphine.

* * *

"It appears that smokers have an altered opioid flow all the time, when compared with non-smokers, and that smoking a cigarette further alters that flow by 20 to 30 percent in regions of the brain important to emotions and craving," says David J. Scott, a graduate student in the U-M Neuroscience Program who will present the results.